
This project will develop and evaluate a periodic counter current (PCC) chromatography and straight-through processing (STP) continuous three-step mAb purification process. Process intensification by implementing continuous or semi-continuous downstream processes in mAb production, for example, can contribute to significant cost-savings and improved throughput. Continuous processing also offers the possibility of increased automation of the process. The project will develop these bioprocesses using model proteins, thereby developing a new, innovative bioprocess platform for the large scale production of mAbs.
Lead investigator | Associate Professor Linda Lua |
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Postdoc | Dr Gary Shooter |
PhD Student | Kristina Pleitt |
Industry Partner | Collaborative project with GE and Patheon. |